Journal: PLoS ONE
Article Title: Comprehensive assessment of tissue and serum parameters of bone metabolism in a series of orthopaedic patients
doi: 10.1371/journal.pone.0227133
Figure Lengend Snippet: A) Percentage of trabecular mass in bone samples A, B) serum tartrate-resistant acid phosphatase type 5b (TRAP5b), C) serum sclerostin, and D) serum C-telopeptide of type-1 collagen (ICTP). Depicted are median values, upper and lower quartiles, minimum and maximum values, and outliers. The outliers are represented as circles for mild outliers (values 1.5–3 times above the upper quartile or below the lower quartile) and as asterisks for extreme outliers (data > 3 times above the upper quartile or below the lower quartile).
Article Snippet: Serum levels of PTH, OPG, sRANKL, AP, osteocalcin, TRAP5b, TP1NP, ICTP, and sclerostin were determined using commercially available enzyme-linked immunosorbent assay (ELISA) kits according to the manufacturer’s instructions: PTH 1–84, human; OPG, human Quidel®; sRANKL, human, high sensitive; TRAP5b, MicroVue; Osteocalcin, MicroVue; Sclerostin (TECOmedical AG, Sissach, Switzerland); Alkaline Phosphatase ELISA Kit (Biotrend Chemikalien GmbH, Cologne, Germany); TP1NP (MyBioSource, San Diego, CA, USA); and human C-telopeptide of procollagen (ICTP) (Biozol, Eching, Germany).
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